Blog Page 17

Importance of Aggregates

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Importance of Aggregates

Aggregate play an important part in providing strength to concrete, the transition zone of concrete is the interfacial region between an aggregate and cement paste and is responsible for providing compressive strength to cement. Care should be taken not to use Maximum size aggregate(MSA) more than 20 mm in your houses while there may be rubble of size as big as 80 to 150 mm. However, in the construction of nuclear power plants, use of rubble is advised since they require thick wall section to act as a shield against radiation.

Aggregate should be round and equiangular in size( they should not be irregular and flaky.

Validation Master Plan in Pharmaceuticals

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The first thing to understand before embarking on the process of creating and following up on a validation master plan, is to understand what it is. Simply put, it is a plan that shows the process of qualifying a facility, outlining the areas that require validating and ultimately, outlining the process of maintaining a facility, once it has been validated. This process is absolutely key in the pharmaceutical industry as there are certain standards to be met, as set up by the government. The process itself may be tedious and long, but worth it in the end.

During audits of your pharmaceutical company, the Food and Drugs Authority (FDA) will look through your validation documents.